Want to know if you had COVID-19?
T cells have the answer.
T-Detect COVID has been shown to have high sensitivity, however in certain circumstances, the test may be negative despite a prior SARS-CoV-2 infection.
Want to know if you had COVID-19?
T cells have the answer.
T-Detect COVID has been shown to have high sensitivity, however in certain circumstances, the test may be negative despite a prior SARS-CoV-2 infection.
Special self-pay test price $150
Additional fees include test authorization ($9) and blood draw
(on-site lab: $60 or in-home: $140).
The price does not represent the usual and customary charge for the T-Detect COVID test and is subject to change. The T-Detect COVID test is FSA/HSA eligible. It is not currently available in the state of New York.
How it works
1. Order
Answer some eligibility questions and submit payment.
Order now.
2. Test authorization
An independent healthcare provider will review your responses and, if appropriate, authorize your test.
3. Blood draw
A certified phlebotomist will draw your blood.
4. Results
Adaptive will process the blood sample and share results with you via a secure email from PWNHealth.
Estimated time for test results is 7-10 days from shipment of blood sample (including 5-7 days for lab processing*).
Adaptive has partnered with PWNHealth, an independent healthcare provider network, to authorize tests, when appropriate.
*Lab processing begins once all required provider and patient information is validated.
Why T cells?
- T cells are the first responders of the adaptive immune system.
- T cell responses persist in the blood long after antibody responses wane.1, 2
- High specificity: T cells can detect 70% of the parts of the virus, while antibodies can only detect 30%.3
T cells vs. antibodies
- In studies, the T-Detect COVID test outperformed leading antibody tests.5
Sensitivity based on Positive Percent Agreement (PPA) with PCR testing.
Sensitivity is the ability of a test to correctly determine if a person has or had the disease.

Frequently asked questions
T cells are the first responders of the adaptive immune system and activate the antibody response. While antibodies to SARS-CoV-2 (the virus that causes the COVID-19 disease) naturally wane and are detectable in the shorter term, T cell responses can persist in the blood long after antibody responses wane.1,2,4
The T-Detect COVID test can detect T cells in a blood sample that can remain for up to several months after symptoms appear.1,2,3
- Zuo J, et al. Robust SARS-CoV-2-specific T-cell immunity is maintained at six months following primary infection. bioRxiv. 2020.
- Adaptive data on file.
- Ng, O, et al. Memory T cell responses targeting the SARS coronavirus persist up to 11 years post-infection. Vaccine. 2016.
- Dalai, D, et al. Clinical Validation of a Novel T-Cell Receptor Sequencing Assay for Identification of Recent or Prior SARS-CoV-2 Infection. medRxiv. 2020.
The T-Detect COVID test can detect an immune response to SARS-CoV-2, the virus that causes COVID-19 disease, to assess recent or past infection. It is not intended for the diagnosis of active/current SARS-CoV-2 infection.
T cells are key players in the adaptive immune system. When the body is invaded by a foreign substance like a virus or bacteria, the immune system begins to rally one of its earliest lines of defense, helper T cells, to join the fight.
Helper T cells may call on their allies to kickstart antibody production to support the fight against the disease. Helper T cells also alert other types of T cells to the presence of foreign invaders to be targeted and destroyed.
After the body has fought off an infection or disease, a small number of T cells remain in the blood. They are called memory T cells and their job is to remember how to ward off these invaders if they ever return.
When the T-Detect COVID test was compared with serology testing:
- In one study, 15 or more days after symptom onset with PCR-diagnosed COVID-19, the T-Detect COVID test identified 94.5% of patients, while leading serology (antibody) tests had a test range from 88.0 -90.4%.1
- In another study, 5+ months after PCR diagnosis, the T-Detect COVID test detected 95% of COVID-19 positive patients, while the serology (antibody) test had a range of 52-71% in detection of COVID-19 positive patients.2
- In studies, the T-Detect COVID test showed a specificity of >99%.1
- Dalai S, et al. Clinical Validation of a Novel T-cell Receptor Sequencing Assay for Identification of Recent or Prior SARS-CoV-2 Infection. medRxiv. 2021.
- Adaptive data on file.
A T cell response is typically detectable in blood several days after initial infection. How long this response lasts post-infection and the implications for immunity are not known. In one study, T cells were shown to persist in the blood for more than six months after initial infection and studies of other coronaviruses show T cell responses can persist for several years.1,2,3
To protect yourself and others, the CDC recommends you wear a mask, stay at least six feet from others whom you don’t live with, avoid crowds and wash your hands often with soap and water for at least 20 seconds (especially after you have been in a public place or after blowing your nose, coughing, or sneezing).
- Zuo J, et al. Robust SARS-CoV-2-specific T-cell immunity is maintained at six months following primary infection. bioRxiv. 2020.
- Channappanavar R, et al. Virus-specific memory CD8 T cells provide substantial protection from the lethal Severe Acute Respiratory Syndrome Coronavirus infection. J Virol. 2014.
- Ng, O, et al. Memory T cell responses targeting the SARS coronavirus persist up to 11 years post-infection. Vaccine. 2016.
The T-Detect COVID test can help you understand if you’ve had a recent or past COVID-19 infection.
The T-Detect COVID test can provide answers in these situations:
- You still have lingering symptoms and wonder if it was COVID-19
- You may have been exposed to COVID-19, but you never got tested and you are concerned that you might have had COVID-19
- You were tested, but you are concerned it may have been a false negative
The test is also appropriate for those interested in supporting COVID-19 research.
The T-Detect COVID test is not meant to diagnose an active infection.
Please consult your doctor regarding whether you should be vaccinated against SARS-CoV-2. As of January 25, 2021, the CDC recommends vaccination for most people, even if they have had a natural infection with SARS-CoV-2.1
- Frequently Asked Questions about COVID-19 Vaccination. Centers for Disease Control and Prevention website. Updated Jan. 25, 2020. Accessed Jan. 26, 2021.https://www.cdc.gov/coronavirus/2019-ncov/vaccines/faq.html
T-Detect COVID is used to detect a recent or past COVID-19 infection. PCR/antigen tests are used to diagnose an active COVID-19 infection. Talk to your doctor about which test is right for you.
There are two reasons this might happen:
- An antibody or antigen (molecular) test could have resulted in a false positive, meaning you did not have the disease and therefore would not have T cells.
- Studies show that T cells typically remain in the body long after antibodies, but it is unclear exactly how long they remain after a COVID-19 infection. Therefore, it is possible to have had COVID-19 and for T cells to have diminished at the time of testing to a number that is not detectable by laboratory tests.
Talk with your doctor if you previously tested positive for COVID-19 and then tested negative for T cells.
Early studies indicate that more than 40% of those who test positive for COVID-19 may be asymptomatic (do not have symptoms). If you have had COVID-19, even if you did not experience symptoms, the immune system would still produce a T cell response.
The T-Detect COVID test is performed via a standard blood draw. You do not need to fast or prepare in any other way before the test is performed.
Order the T-Detect COVID test by answering some eligibility questions and submitting payment. An independent healthcare provider will evaluate your responses and authorize your test order, if appropriate.
If you choose mobile phlebotomy through ExamOne, Adaptive will ship you a test kit and ExamOne will schedule blood draw services via mobile phlebotomy (an in-home blood draw).
If you select a blood draw at a LabCorp patient service center, PWNHealth will place an order with LabCorp. You can schedule an appointment or walk in to any of LabCorp’s patient service centers for a blood draw.
We’ll process the blood sample and share results with you via a secure email from PWNHealth. Estimated time for results is 7-10 days from shipment of blood sample (including 5-7 days for lab processing). Lab processing begins once all required provider and patient information is validated.
Estimated time for results is 7-10 days from shipment of blood sample (including 5-7 days for lab processing). Lab processing begins once all required provider and patient information is validated.
The T-Detect COVID test results are a positive or negative result. A positive result means there was a recent or past exposure to SARS-CoV-2, the virus that causes COVID-19. A negative result indicates that past exposure to SARS-CoV-2 probably did not occur.
We do not currently have information on how the SARS-CoV-2 vaccine may affect the T cell response and the results of the T-Detect COVID test, but we are actively gathering data and will provide updates as information becomes available.
A recent study demonstrated 95% of patients tested positive for T cells up to five months after a confirmed positive PCR test.1 Clinically validated data for T-Detect COVID performance beyond five months is not available yet. Therefore, it is possible that individuals who received a positive PCR result for COVID-19 more than five months ago no longer have sufficient T cells to detect past infection.
- Adaptive data on file.
In some instances, we are not able to definitively determine a positive or negative result. If this happens, your result will say, “no result available.” Call our Clinical Services team at 833-T-DETECT (833-833-8328) to discuss redoing your test at no cost.
Adaptive Biotechnologies follows all state and federal privacy rules, including the Health Information Portability and Accountability Act (HIPAA). Under the CARES Act, we are required to report results to appropriate public authorities.
The T-Detect COVID test is available to individuals at a special self-pay test price of $150, as part of our commitment to supporting testing options during the current public health emergency and to improve our understanding of the role of T cells in COVID-19.
Additional fees include test authorization ($9) and blood draw (on-site lab: $60 or in-home: $140).
The price does not represent the usual and customary customary charge for the T-Detect COVID test and is subject to change. The T-Detect COVID test is FSA/HSA eligible. It is not currently available in the state of New York.
The T-Detect COVID test is not currently covered by insurance. The patient is responsible for blood draw fees, copays for doctor visits, and any additional associated costs. The T-Detect COVID test is FSA/HSA eligible.
Eligible patients may qualify for discounted testing based on their income or medical expenses as part of Adaptive’s patient support program (Adaptive Assist). You can print an Adaptive Assist application and submit it to us at AdaptiveBiotech@mylabbill.com or fax to 440-788-2137. Alternatively, you can contact Adaptive at 855-236-9230 to find out if you might qualify for Adaptive Assist prior to placing your order.
If you have already purchased the test and your application for Adaptive Assist is approved to provide the test at a reduced cost, a refund will be processed to your credit card.
Eligible patients may qualify for discounted testing based on their income or medical expenses as part of Adaptive’s patient support program (Adaptive Assist). You can print an Adaptive Assist application and submit it to us at AdaptiveBiotech@mylabbill.com or fax to 440-788-2137. Alternatively, you can contact Adaptive at 855-236-9230 to find out if you might qualify for Adaptive Assist prior to placing your order.
If you have already purchased the test and your application for Adaptive Assist is approved to provide the test at a reduced cost, a refund will be processed to your credit card.
Contact us at 833-T-DETECT (833-833-8328) within 24 hours if you wish to change or cancel your order. No refunds or cancellations can be made after 24 hours.
If we are unable to provide a laboratory report after you submit your blood sample, a refund will automatically be issued to the credit card you used and will be net of any costs for telehealth, phlebotomy, or other processing fees deducted. Contact us at 833-T-DETECT (833-833-8328) or email us at t-detectinquiries@adaptivebiotech.com.
Mobile phlebotomy is a mobile blood draw service in which a certified phlebotomist (someone trained to draw blood) visits your home to collect a blood sample.
ExamOne is a national mobile phlebotomy service provider that Adaptive Biotechnologies has partnered with to help provide blood draw services to patients.
LabCorp is one of the largest clinical network laboratories in the U.S., with approximately 2,000 Patient Service Centers. If you select a LabCorp blood draw, a licensed phlebotomist (blood draw technician) will draw your blood at the LabCorp location you select after ordering the T-Detect COVID test.
PWNHealth is an independent healthcare provider network that provides oversight services to patients in connection with the laboratory testing that you have requested. PWNHealth and its services are independent from the laboratory and company from which you requested and registered for the T-Detect COVID test.
At this time, the T-Detect COVID test is available to be prescribed by healthcare professionals in all U.S. states except for the state of New York. The state of New York requires laboratories conducting clinical testing on specimens from New York to obtain a special clinical laboratory permit. Adaptive is actively working with the proper regulatory bodies to gain the necessary approvals and we expect to provide access to the test in New York in early 2021. For updates on when the test is available to be prescribed in the state of New York, sign up for email updates.
The T-Detect COVID test is only available in the U.S. and is not available in U.S. Territories.
Currently, the T-Detect COVID assay has not been cleared or approved by the FDA for Emergency Use Authorization. However, the T-Detect COVID assay is available for use as a CLIA-validated laboratory-developed test (LDT). Specific guidance around use and interpretation of this test may change with future FDA guidance on T cells as they relate to COVID-19, including EUA requirements.
You can visit CDC.gov and/or your county’s public health department website to learn more about COVID-19, testing options and vaccination schedules.
In vitro diagnostic for prescription use only. This test has not been cleared or approved by the FDA. The T-Detect COVID assay is available for use as a CLIA-validated laboratory developed test (LDT). T-Detect COVID is not indicated for use in patients under age 18.
For Physicians
The T-Detect COVID test can capture past COVID-19 infections that may be missed by serology testing.
For Employers
The T-Detect COVID test can help your employees get the answers they need.
For Researchers
The T-Detect COVID test can support your research due to its high sensitivity and specificity.
References
- Tay MZ, et al. The trinity of COVID-19: immunity, inflammation and intervention. Nat Rev Immunol. 2020.
- Ng O, et al. Memory T cell responses targeting the SARS coronavirus persist up to 11 years post-infection. Vaccine. 2016.
- Zuo J, et al. Robust SARS-CoV-2-specific T-cell immunity is maintained at 6 months following primary infection. bioRxiv. 2020.
- Channappanavar R, et al. Virus-specific memory CD8 T cells provide substantial protection from lethal severe acute respiratory syndrome coronavirus infection. J Virol. 2014.
- Dalai S, et al. Clinical Validation of a Novel T-cell Receptor Sequencing Assay for Identification of Recent or Prior SARS-CoV-2 Infection. medRxiv. 2021.
- Adaptive data on file.