Frequently asked questions

T cells

What are T cells?

T cells, which are a type of white blood cell, are the first responders of the adaptive immune system. When you’re exposed to a virus or bacteria, T cells jump into action by killing infected cells and stimulating antibody production. After your body fights off an infection or disease, a small number of T cells remain in the blood—often even after antibodies have waned—to remember how to ward off these invaders if they ever return.1,2

  1. Zou J., et al. “Robust SARS-CoV-2-specific T cell Immunity Is Maintained at 6 Months Following Primary Infection.” Nat Immunol. 2021.
  2. Dalai S., et al. “Clinical Validation of a Novel T-cell Receptor Sequencing Assay for Identification of Recent or Prior SARS-CoV-2 Infection.” medRxiv. 2021.

T-Detect Lyme

What is Lyme disease?

Lyme disease, the most common tick-borne illness that occurs throughout the United States, is an infectious disease caused by the bacterium Borrelia burgdorferi and spread from the bite of an Ixodes tick (also called a deer tick or black-legged tick).

T-Detect COVID

What is COVID-19?

COVID-19 (coronavirus disease 2019) is a contagious respiratory viral infection caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). It was first identified in late 2019 and is responsible for the COVID-19 pandemic.

Blood draw

How do I prepare for my T-Detect blood draw?

The T-Detect test is performed using a standard blood draw. You do not need to fast or prepare in any other way before the test is performed.

Cost and payment

Is T-Detect covered by insurance?

T-Detect is not currently covered by insurance. It is FSA/HSA eligible.

Eligible patients may qualify for discounted testing based on their income or medical expenses as part of the Adaptive Assist Patient Support Program. There are two ways to submit an Adaptive Assist application:

  • Call Patient Support at 855-236-9230, Monday through Thursday between 9 a.m. and 7 p.m. or Fridays between 9 a.m. and 5 p.m. (Eastern Time).
  • Print an application and mail it to:

Adaptive Biotechnologies
Dept LA 24084
Pasadena, CA 91185-4084

Patient ordering

How do I order T-Detect?

T-Detect Lyme is only available from your healthcare provider. Share this doctor discussion guide and instructions for ordering T-Detect with your doctor.

For T-Detect COVID, you can order the test by answering some eligibility questions and submitting payment. An independent healthcare provider will evaluate your responses and authorize your test order, if appropriate.

If you select Labcorp for your blood draw, you can schedule an appointment online or walk into any of Labcorp’s Patient Service Centers for a blood draw. Labcorp will have the appropriate materials to collect the blood sample, so you will not receive a test collection kit. Labcorp blood draw services are not available in Hawaii, North Dakota or Vermont.

If you choose mobile phlebotomy (an in-home blood draw) through ExamOne, Adaptive Biotechnologies will ship you a test collection kit and ExamOne will call you within two days of test authorization to schedule an appointment.

Healthcare providers

How can a provider start offering T-Detect?

Contact Clinical Services, Monday through Friday between 8:30 a.m. and 8 p.m. (Eastern Time) at 833-T-DETECT (833-833-8328) or to start the onboarding process.


What is ExamOne?

ExamOne is a national mobile phlebotomy service provider that Adaptive Biotechnologies has partnered with to provide mobile blood draw services to patients.

Mobile phlebotomy is a mobile blood draw service in which a certified phlebotomist, someone trained to draw blood, visits your home or other location to collect a blood sample.

Real world data study

What is the purpose of the real-world data study?

Adaptive has developed clinical tests intended to identify an immune response to a given disease. The goal of this study is to provide real-world data to evaluate and improve clinically available T-Detect tests based on your health information, as well as to provide data for future T-Detect tests.


Is my information kept private?

Adaptive Biotechnologies follows all state and federal privacy rules, including the Health Insurance Portability and Accountability Act (HIPAA).


Can children get a T-Detect test?

T-Detect is only available to those age 18 or older. The test has not been validated for children under the age of 18; therefore, Adaptive Biotechnologies cannot accept or process orders for those under age 18.


Who can I contact if I have a question about T-Detect?

Contact Clinical Services Monday through Friday between 8:30 a.m. and 8 p.m. (Eastern Time) at 833-T-DETECT (833-833-8328) or

T-Detect COVID is not FDA cleared or approved. It is authorized for emergency use under an Emergency Use Authorization (EUA). 

Testing of venous whole blood using K2 EDTA specimens is limited to laboratories designated by Adaptive Biotechnologies Corporation that are certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA), 42 U.S.C. §263a, and meets the requirements to perform high complexity tests as described in the T-Detect COVID Test Standard Operating Procedure that was reviewed by the FDA under this EUA.

This test has been authorized only for detecting and identifying the presence of an adaptive T-cell immune response to SARS-CoV-2, not for any other viruses or pathogens.

The performance of this test was established based on the evaluation of a limited number of clinical specimens. Clinical performance has not been established with all circulating variants but is anticipated to be reflective of the prevalent variants in circulation at the time and location of the clinical evaluation. Performance at the time of testing may vary depending on the variants circulating, including newly emerging strains of SARS-CoV-2 and their prevalence, which change over time.  

The emergency use of this test is only authorized for the duration of the declaration that circumstances exist justifying the authorization of emergency use of in vitro diagnostics for detection and/or diagnosis of COVID-19 under Section 564(b)(1) of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. § 360bbb3(b)(1), unless the declaration is terminated or authorization is revoked sooner.

T-Detect Lyme is for prescription use only. For in vitro diagnostic use only. The CLIA laboratory-developed test (LDT) service has not been cleared or approved by the U.S. Food and Drug Administration (FDA) for this intended use.

T-Detect  is not indicated for use in patients under age 18.